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Scores sign up for breast cancer research project

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Carika Weldon is leading the Caribbean Whole Genome Breast Cancer Research Pilot Study. (Photograph supplied.)

Almost 140 people have been registered to take part in a groundbreaking research project into genetic factors influencing breast cancer in the Caribbean population.

Bermudian-based CariGenetics, a genomic laboratory run by Carika Weldon, launched an appeal for volunteers to take part in the Caribbean Whole Genome Breast Cancer Research Pilot Study.

The laboratory said 62 eligible participants were recruited from those who have registered, having completed their consent interviews and given blood samples. All 62 samples have had DNA extracted and are ready for genetic sequencing.

Khamani Fox, the clinical operations manager at CariGenetics, said: “We are thrilled with the community's enthusiastic response to our study.

An update from CariGenetics on the Caribbean Breast Cancer Study shows how many people have been recruited so far (Image courtesy of CariGenetics)

“This is a monumental step towards understanding the genetic factors influencing breast cancer in the Caribbean population.

“However, we still require additional participants and encourage those who meet the criteria to join us in this transformative initiative.”

A pressing issue that needs immediate attention

The Caribbean Breast Cancer Whole Genome Pilot Study is an initiative by CariGenetics to understand the genetic differences in breast cancer among women of Caribbean ancestry.

By conducting whole genome sequencing, CariGenetics aims to uncover unique genetic markers that could lead to earlier detection, better prevention strategies, and more effective treatments.

Breast cancer affects women worldwide, but not all women are affected equally. Black women, particularly those of Caribbean ancestry, are more likely to die from breast cancer than any other group.

CariGenetics’s website said the disparity “is a pressing issue that needs immediate attention”.

It explained: “Our research aims to address this problem head-on and make a significant difference in the lives of these women.

“Studies indicate a pressing need to dive deeper into the unique genetic markers distinguishing Caribbean women.

“At CariGenetics, we’re at the forefront of this vital research.”

CariGenetics has two groups for the research, a control group and a patient group.

The laboratory has decided to open five more spots in its control group and patient group, meaning it will have 55 in each. Originally it aimed for 100 volunteers.

Of the people eligible recruited participants signed up so far, 42 are in the patient group and 20 are in the control group.

The next round of recruitment will be held from December 11 to 15.

To be eligible for the control group, participants should have no history of cancer in either themselves or first-degree relatives such as parents, siblings or children, have full insurance coverage and have four grandparents of Caribbean ancestry, including Bermudian.

To match the age of diagnosis in the patient group, CariGenetics is looking to fill specific age-bracket spots in the control group: 13 women aged 40 to 49, three women aged 50 to 59, four women aged 60 to 69 and two women aged 70 to 79.

Ms Fox added: “Participation is 100 per cent voluntary and will not impact current or previous treatment plans.

“All information is anonymised and will not be given to external parties without the participant's consent.

“Participants may withdraw from the study at any time without penalty or loss of benefit.”

People interested in volunteering can call Dr Weldon on 500-1982 or apply here.

The Caribbean Breast Cancer Whole Genome Pilot Study provided by CariGenetics is supported through funding from the Innovation Programme managed by the Bermuda Health Council and has received approval from the Bermuda Hospitals Board Research Ethics Committee.

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Published November 21, 2023 at 1:48 pm (Updated November 22, 2023 at 9:59 am)

Scores sign up for breast cancer research project

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